Target-Controlled Anesthesia Reduces Postoperative Delirium in Spinal Surgical Patients: A Prospective Pilot Study

The aim of this pilot study was to examine the effect combined target-controlled anesthesia and manually controlled on incidence postoperative delirium (POD) in patients undergoing spinal surgery. All were enrolled before surgery divided into 2 groups at random: one group received sevoflurane inhalation sufentanil infusion (S-S TCI group), whereas other MCI group). Data related preoperative factors, perioperative data retrospectively collected. Compared with S-S group, dosage vasoactive drugs after surgery, recovery time, time cannula removal, POD significantly decreased (P < 0.05). Overall, appeared 81 (16.8%) by day 3. Multiple regression analysis showed that blood loss risk factors for patients. Therefore, prophylactic transfusion phenylephrine can reduce presence hypotension. Target-controlled may improve quality as well surgical These results provide clinical evidence improving prevention, diagnosis, management POD.